Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma
نویسندگان
چکیده
منابع مشابه
Human papillomavirus detection in head and neck squamous cell carcinoma
Squamous cell carcinomas of the head and neck (HNSCC) are a frequent diagnosis in anatomic pathology practice. Tobacco use and heavy alcohol consumption are known risk factors for HNSCC but in other cases human papillomavirus (HPV) is linked to carcinogenesis. HPV proteins E6 and E7 promote oncogenesis by blocking the action of p53 and pRB, respectively. An absence of p53 mutations in addition ...
متن کاملMulticentric human papillomavirus-associated head and neck squamous cell carcinoma.
BACKGROUND The purpose of this study was to present the clinicopathological features of a series of patients with human papillomavirus (HPV)-associated head and neck second primary tumors. METHODS Patients with HPV-associated head and neck second primary tumors from 3 centers were identified. HPV infection was evaluated using p16 by immunohistochemistry (IHC), high-risk HPV DNA by in situ hyb...
متن کاملHuman Papillomavirus-associated Head and Neck Squamous Cell Carcinoma Major
Head and neck squamous cell carcinoma (HNSCC) which includes the oral cavity, oropharynx and larynx is the sixth most common cancer worldwide with an estimated 633,000 incident cases and 335,000 deaths annually[1,2]. Human papillomavirus (HPV) is specifically associated with squamous cell carcinomas (SCC) of the oropharynx which encompasses the base of the tongue, lingual and palatine tonsils a...
متن کاملAssociation between Human Papillomavirus Infection and Risk of Prostate Cancer
Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases worldwide and is the etiological agent of cervical and other anogenital malignancies. Since HPVs have been shown to possess oncogenic potential, an association between HPV infection and prostatic cancer (PCa) has been suggested. There are conflicting reports on the impact of HPV infection on the deve...
متن کاملHuman papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck.
BACKGROUND Oncogenic human papillomaviruses (HPVs), especially HPV type 16 (HPV-16), cause anogenital epithelial cancers and are suspected of causing epithelial cancers of the head and neck. METHODS To examine the relation between head and neck cancers and HPVs, we performed a nested case-control study within a joint Nordic cohort in which serum samples were collected from almost 900,000 subj...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2008
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-08-0498